Search results for " Cystectomy"

showing 10 items of 31 documents

The clinical use of statistical permutation test methodology: a tool for identifying predictive variables of outcome.

2015

<b><i>Objectives:</i></b> To identify the predictive variables affecting the outcome after radical surgery for bladder cancer by a newer statistical methodology, i.e. nonparametric combination (NPC). <b><i>Methods:</i></b> A multicenter study enrolled 1,312 patients who had undergone radical cystectomy for bladder cancer in 11 Italian oncological centers from January 1982 to December 2002. A statistical analysis<b> </b>of their medical history and diagnostic, pathological and postoperative variables was performed using a NPC test. The<b> </b>patients were included in a comprehensive database with medical history and cli…

AdultMalemedicine.medical_specialtyUrologyStatistics as TopicHydronephrosisnonparametric combinationCystectomyOutcome (game theory)Statistics NonparametricBladder cancer; Permutation test; PrognosisSettore MED/24 - UrologiaBladder cancer Prognosis Permutation testPredictive Value of TestsResamplingMedicineHumansPermutation testRadical surgeryIntensive care medicineAgedNeoplasm StagingRetrospective StudiesAged 80 and overCarcinoma Transitional CellBladder cancerbusiness.industryBladder cancerProstatePermutation testsMiddle Agedmedicine.diseasePrognosisradical surgery for bladder; nonparametric combinationradical surgery for bladderSurgeryPatient Outcome Assessmentbladder cancer; Prognosis; Permutation testsItalyUrinary Bladder NeoplasmsBladdder Cancer Cystectomy outcome statistical methodologyData Interpretation StatisticalLymphatic MetastasisMultivariate AnalysisFemalePredictive variablesradical surgery for bladder nonparametric combinationbusiness
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Conservative management of T1G3 transitional cell carcinoma of the bladder. Risk factor analysis in 165 selected patients

2003

INTRODUCTION AND OBJECTIVE: The management of TlG3 transitional cell carcinoma of the bladder (TCCB), is still controversial. Some Authors support an immediate radical cystectomy. BCG is considered the treatment of choice. Limited encouraging experiences are reported with intravesical chemotherapy. Objectives; Evaluating a selected population of 165 patients with TlG3 TCCB, in absence of Tis, treated conservatively with TUR plus adjuvant intravesical therapy. METHODS: Between January 1976 and December 1999, 165 patients with TlG3 bladder tumors were treated by TUR plus adjuvant intravesical therapy. Patients with previuos T1G3, Tis, more than 3 tumors or greater than 3 em were excluded. A s…

BCGradical cystectomytransitional cell carcinoma of the bladder (TCCB)Settore MED/24 - Urologia
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Preoperative favourable characteristics in bladder cancer patients cannot substitute the necessity of extended lymphadenectomy during radical cystect…

2016

Bladder Cancer CystectomySettore MED/24 - Urologia
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Quality of life following urinary diversion: Orthotopic ileal neobladder versus ileal conduit. A multicentre study among long-term, female bladder ca…

2019

Abstract Introduction Women undergoing radical cystectomy (RC) followed by urinary diversion (UD) for bladder cancer experience a substantial reduction in health-related quality of life (HRQOL). At present, studies comparing long-term QOL outcomes for different UD methods, needed to inform evidence-based choices of bladder reconstruction for female patients, are sparse. Our objective was to compare two common UD methods in terms of their HRQOL outcomes in women. Materials and methods We retrospectively analysed HRQOL in 73 consecutive female bladder cancer patients having undergone orthotopic ileal neobladder (IONB, N = 24) or ileal conduit (IC, N = 49) following RC between 2007 and 2013 in…

Bladder cancer; Ileal conduit; Orthotopic neobladder; Quality of life; Radical cystectomy; Women;Time Factorsmedicine.medical_treatment030232 urology & nephrologyUrinary DiversionBladder cancer; Ileal conduit; Orthotopic neobladder; Quality of life; Radical cystectomy; Women; Adult; Aged; Aged 80 and over; Cancer Survivors; Cross-Sectional Studies; Female; Follow-Up Studies; Humans; Ileum; Italy; Middle Aged; Surveys and Questionnaires; Survival Rate; Time Factors; Urinary Bladder Neoplasms; Urinary Diversion; Quality of Life; Urinary Reservoirs Continent; Surgery; Oncology0302 clinical medicineCancer SurvivorsQuality of lifeSurveys and QuestionnairesOrthotopic neobladder80 and overSurveys and QuestionnaireStage (cooking)Aged 80 and overSettore MED/24 - UROLOGIABladder cancerUrinary Reservoirs ContinentGeneral MedicineMiddle AgedhumanitiesSurvival RateIleal conduitItalyOncology030220 oncology & carcinogenesisUrinary Bladder NeoplasmFemaleCancer SurvivorUrinary ReservoirsHumanQuality of lifeAdultmedicine.medical_specialtyTime FactorFollow-Up StudieCystectomy03 medical and health sciencesIleumInternal medicinemedicineHumansWomenPathologicalAgedCross-Sectional StudieBladder cancerbusiness.industryUrinary diversionCancermedicine.diseaseRadiation therapyRadical cystectomyContinentCross-Sectional StudiesBladder cancer; Ileal conduit; Orthotopic neobladder; Quality of life; Radical cystectomy; WomenUrinary Bladder NeoplasmsSurgerybusinessFollow-Up StudiesEuropean Journal of Surgical Oncology
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THE ROLE OF PERI-OPERATIVE BLOOD TRANSFUSION ON CANCER SPECIFIC AND OVERALL MORTALITY AFTER RADICAL CYSTECTOMY FOR BLADDER CANCER

2014

Only few studies investigated the impact of the peri-operative blood transfusion (PBT) rate on both cancerspecific (CSM) and overall mortality (OM) after radical cystectomy (RC) for bladder cancer (Bca). To date, no study has taken into account the possible prognostic role of the pre-operative hemoglobin level (Hb). The aim of this study was to evaluate the impact of both pre-operative Hb level and PBT rate on CSS and OS of patients who underwent RC. Materiali e metodi The study cohort included 1575 patients treated with RC for BCa between 1990 and 2012 at a single tertiary referral center. Complete clinical, pathological and follow up-data was available for all the patients. Kaplan- Meier …

Blood transfusion radical cystectomy prognosis bladder cancerSettore MED/24 - Urologia
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Robot-Assisted, Laparoscopic, and Open Radical Cystectomy: Pre-Operative Data of 1400 Patients From The Italian Radical Cystectomy Registry.

2022

The Italian Radical Cystectomy Registry (RIC) is an observational prospective study aiming to understand clinical variables and patient characteristics associated with short- and long-term outcomes among bladder cancer (BC) patients undergoing radical cystectomy (RC). Moreover, it compares the effectiveness of three RC techniques - open, robotic, and laparoscopic.From 2017 to 2020, 1400 patients were enrolled at one of the 28 centers across Italy. Patient characteristics, as well as preoperative, postoperative, and follow-up (3, 6, 12, and 24 months) clinical variables and outcomes were collected.Preoperatively, it was found that patients undergoing robotic procedures were younger (p.001) a…

Cancer ResearchItaly; RIC; multicenter; radical cystectomy; urinary bladder neoplasmsItalyOncologyRICmulticenterurinary bladder neoplasmsradical cystectomySettore MED/24 - UrologiaFrontiers in oncology
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EGFR CELL EXPRESSION IN BLADDER WASHINGS AS A RISK MARKER TOOL IN NON MUSCLE-INVASIVE BLADDER CANCER. PRELIMINARY EXPERIENCE

2017

EGFR bladder cancer T1HG cystectomySettore MED/24 - Urologia
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Quality-of-Life Outcomes in Female Patients With Ileal Conduit or Orthotopic Neobladder Urinary Diversion: 6-Month Results of a Multicenter Prospecti…

2022

Radical cystectomy (RC) often affects patients’ life as this surgery is a traumatic and invasive event for the patients, with drawbacks on their daily, social, working, and sex life. Such changes in the quality of life (QoL) of patients are commonly studied through retrospective clinical evaluations and rarely with longitudinal studies. To date, studies focusing on functional outcomes, sexual function, and health-related QoL for female patients are lacking. We evaluated 37 patients using EORTC QLQ-C30 (QLQ-30) and Short-Form 36 (SF-36) questionnaires, before and after surgery, at 3 and 6 months of follow-up. The mean values for the emotional functioning in QLQ-C30 as well as the mental heal…

HRQOLCancer ResearchfemaleOncologyHRQOL; bladder cancer; female; radical cystectomy; urinary diversionurinary diversionbladder cancerbladder cancer female radical cystectomy HRQOL urinary diversionradical cystectomyhumanities
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Quality of life in patients with bladder cancer undergoing ileal conduit: A comparison of women versus men

2018

Background/Aim: Studies comparing health-related quality of life (HR-QoL) between patients who underwent radical cystectomy (RC) and those who underwent a different form of urinary diversion has not reached yet univocal and reliable conclusions. The aim of our study was to evaluate bladder-specific long-term HR-QoL after radical cystectomy and ileal conduit. Patients and Methods: A multicenter study was carried out on 145 consecutive patients (112 males and 33 females) undergoing RC and ileal conduit (IC). HR-QoL assessment was conducted using Italian versions of European Organisation for Research and Treatment of Cancer QLQ-C30 and EORTC BLM-30 questionnaires. Results: Our data showed that…

MaleGenetics and Molecular Biology (all)Cancer Researchmedicine.medical_treatment030232 urology & nephrologySex FactorUrinary DiversionBiochemistrySettore MED/24 - UrologiaBladder cancer; ileal conduit; quality of life; Orthotopic neobladder0302 clinical medicineQuality of lifeSurveys and QuestionnairesOutcome Assessment Health CareOrthotopic neobladderSurveys and QuestionnaireUrinary bladderSettore MED/24 - UROLOGIABladder cancerMiddle AgedhumanitiesBladder cancer; Ileal conduit; Orthotopic neobladder; Quality of life; Radical cystectomy; Biochemistry Genetics and Molecular Biology (all); Pharmacologymedicine.anatomical_structureIleal conduit030220 oncology & carcinogenesisUrinary Bladder NeoplasmFemaleResearch ArticleHumanQuality of lifemedicine.medical_specialtyBladder cancer; Ileal conduit; Orthotopic neobladder; Quality of life; Radical cystectomy; Aged; Female; Humans; Male; Middle Aged; Outcome Assessment (Health Care); Sex Factors; Surveys and Questionnaires; Urinary Bladder; Urinary Bladder Neoplasms; Urinary Diversion; Quality of Life; Biochemistry Genetics and Molecular Biology (all); PharmacologyUrinary BladderGeneral Biochemistry Genetics and Molecular BiologyCystectomy03 medical and health sciencesOutcome Assessment (Health Care)Sex FactorsInternal medicinemedicineHumansIn patientAgedPharmacologyBladder cancerBiochemistry Genetics and Molecular Biology (all)business.industryUrinary diversionCancermedicine.diseaseRadical cystectomyUrinary Bladder NeoplasmsBladder cancer; ileal conduit; orthotopic neobladder; quality of life; radical cystectomybusinessSexual function
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High-Grade T1 on Re-Transurethral Resection after Initial High-Grade T1 Confers Worse Oncological Outcomes: Results of a Multi-Institutional Study

2018

The aim of this multicenter study was to investigate the prognostic impact of residual T1 high-grade (HG)/G3 tumors at re-transurethral resection (TUR of bladder tumor) in a large multi-institutional cohort of patients with primary T1 HG/G3 bladder cancer (BC).

MaleTime Factorsmedicine.medical_treatment:Medicina Básica [Ciências Médicas]Treatment outcomeBladder cancer; High risk; High-grade; Second look resection; Transurethral resection of bladder tumor; Aged; Aged 80 and over; Carcinoma Transitional Cell; Cystectomy; Disease Progression; Disease-Free Survival; Female; Follow-Up Studies; Humans; Male; Middle Aged; Neoplasm Recurrence Local; Prognosis; Progression-Free Survival; Recurrence; Regression Analysis; Time Factors; Treatment Outcome; Urinary Bladder Neoplasms; Urologic Surgical Procedures030232 urology & nephrologySettore MED/24 - Urologia0302 clinical medicineRecurrenceHigh-grade80 and overAged 80 and overTransurethral resection of bladder tumorCARCINOMA TRANSITIONAL CELLHigh riskBladder cancerFollow up studiesMiddle AgedPrognosisProgression-Free Survival3. Good healthScholarshipTreatment OutcomeLocal030220 oncology & carcinogenesisCiências Médicas::Medicina BásicaUrinary Bladder NeoplasmDisease ProgressionRegression AnalysisUrologic Surgical ProceduresFemaleSecond look resectionHumanmedicine.medical_specialtyTime FactorPrognosiUrologyBladder cancer; High risk; High-grade; Second look resection; Transurethral resection of bladder tumorCystectomyRegression AnalysiDisease-Free SurvivalResectionFollow-Up StudieCystectomy03 medical and health sciencesbladder cancer; high risk; high-grade; second look resection; transurethral resection of bladder tumor; aged; aged 80 and over; carcinoma transitional cell; cystectomy; disease progression; disease-free survival; female; follow-up studies; humans; malemedicineHumansProgression-free survivalAgedCarcinoma Transitional CellScience & Technologybusiness.industryGeneral surgeryDisease progressionCarcinomaNeoplasm RecurrenceUrinary Bladder NeoplasmsUrologic Surgical ProcedureTransitional CellTransurethral resection of bladder tumor.Neoplasm Recurrence LocalbusinessFollow-Up Studies
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